{"id":2924,"date":"2022-03-16T22:43:57","date_gmt":"2022-03-16T14:43:57","guid":{"rendered":"https:\/\/fastonetech.com\/blog\/?p=2924"},"modified":"2024-05-09T13:34:33","modified_gmt":"2024-05-09T05:34:33","slug":"aiddcaddjd","status":"publish","type":"post","link":"https:\/\/fastonetech.com\/blog\/aiddcaddjd\/","title":{"rendered":"\u521b\u65b0\u836f\u7814\u53d1\u4e5d\u6b7b\u4e00\u751f\uff0cCADD\/AIDD\u662f\u7b54\u6848\u5417\uff1f"},"content":{"rendered":"\n
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3\u3001\u86cb\u767d\u4e0e\u86cb\u767ddocking\u53ef\u4ee5\u5728\u5e73\u53f0\u4e2d\u8fd0\u884c\u5417\uff1f<\/strong>DOCK\u53d1\u5c55\u5230\u73b0\u5728\u6574\u5408\u591a\u6b65\u9aa4\u7684HADDOCK\u3001ClusPro\u3001SwamDock\u3001RosettaDock\u7b49\u7b49\uff0c\u8be5\u9886\u57df\u7684\u7b97\u6cd5\u4e0d\u65ad\u5730\u5347\u7ea7\u8fed\u4ee3\u3002\u5e73\u53f0\u4e5f\u80fd\u591f\u5f88\u65b9\u4fbf\u5730\u96c6\u6210\u76f8\u5173\u8f6f\u4ef6\uff0c\u63d0\u4f9b\u9a8c\u8bc1\u73af\u5883\u3002 <\/p>\n\n\n\n

4\u3001\u60f3\u8981\u901a\u8fc7\u5e73\u53f0\u7b5b\u9009\u4e00\u4e9b\u7279\u5b9a\u7ed3\u6784\u7684\u5206\u5b50\uff0c\u662f\u5426\u53ef\u4ee5\u4f18\u5316\u5316\u5408\u7269\u5e93\uff1f<\/strong>\u5982\u679c\u60a8\u80fd\u591f\u63d0\u4f9b\u786e\u5207\u4fe1\u606f\uff0c\u53ef\u4ee5\u4e00\u540c\u8ba8\u8bba\u4f18\u5316\u3002\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u51c6\u5907\u4e86\u5f88\u591a\u5f00\u6e90\u7684\u5206\u5b50\u5e93\u4f9b\u5927\u5bb6\u4f7f\u7528\uff0c\u73b0\u5728\u5df2\u652f\u6301Zinc\u3001Drugbank\u3001Maybridge\u3001Enamine\u7b49\u3002 <\/p>\n\n\n\n

5\u3001\u76ee\u524d\u5e73\u53f0\u4e2d\u662f\u5426\u6709\u81ea\u5efa\u7684\u5316\u5408\u7269\u6570\u636e\u5e93\uff1f<\/strong>
CADD\u7814\u7a76\u8fc7\u7a0b\u4e2d\uff0c\u4e0d\u8bba\u662f\u9776\u70b9\u7684\u53d1\u73b0\u548c\u4f18\u5316\u3001\u8fd8\u662f\u5148\u5bfc\u5316\u5408\u7269\u7684\u53d1\u73b0\u548c\u4f18\u5316\uff0c\u5f00\u6e90\u7684\u5206\u5b50\u5e93\u662f\u5fc5\u4e0d\u53ef\u5c11\u7684\u57fa\u7840\u6570\u636e\u3002\u76ee\u524d\u5f00\u6e90\u7684\u5206\u5b50\u5e93\u6570\u636e\u5206\u6563\u5404\u5730\uff0c\u4e0b\u8f7d\u7f13\u6162\uff0c\u683c\u5f0f\u4e0d\u7edf\u4e00\uff0c\u66f4\u65b0\u9891\u7387\u4e0d\u7b49\uff0c\u5bfc\u81f4\u65e0\u6cd5\u7edf\u4e00\u4f7f\u7528\u548c\u7ba1\u7406\uff0c\u6570\u636e\u8d44\u4ea7\u4f5c\u7528\u53d1\u6325\u6709\u9650\u3002\u6240\u4ee5\u6211\u4eec\u6784\u5efa\u4e86fastone\u81ea\u6709\u7684\u5206\u5b50\u5e93\uff0c\u5e76\u505a\u597d\u4e86\u8fdb\u4e00\u6b65\u7684\u6570\u636e\u51c6\u5907\u3002
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1\u3001\u6570\u636e\u9884\u5904\u7406\uff0c\u5408\u5e76\u6216\u683c\u5f0f\u8f6c\u6362\uff1b
2\u3001\u6570\u636e\u540e\u5904\u7406\uff0c\u53bb\u91cd\u6216\u529b\u573a\u4f18\u5316\u3002<\/p>\n\n\n\n

 6\u3001\u4f60\u4eec\u53ef\u4ee5\u534f\u52a9\u505a\u5c0f\u5206\u5b50\u8bbe\u8ba1\u5417\uff1f<\/strong>
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 7\u3001\u57fa\u56e0\u6570\u636e\u91cf\u5f88\u5927\uff0c\u5e73\u53f0\u6709\u4ec0\u4e48\u597d\u7684\u89e3\u51b3\u529e\u6cd5\uff1f<\/strong>
\u5bf9\u4e8eGB\u7ea7\u522b\u7684\u589e\u91cf\u6570\u636e\uff0c\u6211\u4eec\u652f\u6301\u4ee5\u6df7\u5408\u4e91\u7ec4\u7f51\u4e13\u7ebf\u7684\u65b9\u5f0f\u4f18\u5316\u4e0a\u4f20\u7ebf\u8def\u3002\u4f20\u8f93\u901a\u9053\u4f7f\u7528DM\u5de5\u5177\uff0c\u652f\u6301\u5168\u81ea\u52a8\u5316\u6570\u636e\u4e0a\u4f20\uff0c\u53ef\u5145\u5206\u5229\u7528\u5e26\u5bbd\uff0c\u5e2e\u52a9\u7528\u6237\u5feb\u901f\u4e0a\u4f20\u3001\u4e0b\u8f7d\u6d77\u91cf\u6570\u636e\u3002
\u5bf9\u4e8ePB\u7ea7\u522b\u7684\u5b58\u91cf\u6570\u636e\uff0c\u5efa\u8bae\u901a\u8fc7\u79bb\u7ebf\u65b9\u5f0f\u5feb\u901f\u4f20\u8f93\u3002 <\/p>\n\n\n\n

8\u3001\u6700\u7ec8\u7ed3\u679c\u80fd\u5426\u5728\u7ebf\u53ef\u89c6\u5316\u67e5\u770b\uff1f<\/strong>
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\"\"<\/figure>\n\n\n\n

<\/p>\n\n\n\n

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9\u3001\u4e91\u5e73\u53f0\u80fd\u8986\u76d6\u5230\u6211\u5e38\u7528\u7684\u8f6f\u4ef6\u5417\uff1f<\/strong>\u6211\u4eec\u652f\u6301\u5e38\u7528\u7684\u751f\u7269\/\u5316\u5b66\u8ba1\u7b97\u7c7b\u5e94\u7528\uff0c\u5305\u62ec\uff1a\u751f\u7269\u5316\u5b66\u4e0e\u5206\u5b50\u751f\u7269\u5b66\/\u5316\u5b66\u5de5\u7a0b\/\u751f\u7269\u5316\u5b66\/\u5e94\u7528\u5316\u5b66\/\u751f\u7269\u5de5\u7a0b\/\u836f\u7269\u5316\u5b66\/\u5206\u6790\u5316\u5b66\/\u7269\u7406\u5316\u5b66\/\u9ad8\u5206\u5b50\u5316\u5b66\u4e0e\u7269\u7406\u3002 <\/p>\n\n\n\n

10\u3001\u5177\u4f53\u6765\u8bf4\uff0c\u652f\u6301\u54ea\u4e9b\u751f\u7269\/\u5316\u5b66\u8ba1\u7b97\u7c7b\u5e94\u7528\/\u5de5\u5177\uff1f<\/strong>\u6211\u4eec\u652f\u6301\u51e0\u4e4e\u6240\u6709\u7684\u751f\u7269\/\u5316\u5b66\u8ba1\u7b97\u7c7b\u5e94\u7528\/\u5de5\u5177\uff0c\u5305\u62ec\uff1aAutoDockVina\u3001Amber\u3001FastQC\u3001DeltaVina\u3001GATK\u3001Gromacs\u3001Schr\u00f6dinger\u3001NetMHC\u3001Rosetta\u3001BCFtools\u7b49\u3002<\/p>\n\n\n\n

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11\u3001\u4f60\u4eec\u652f\u6301Alphafold\u5417\uff1f<\/strong>
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12\u3001\u6211\u4eec\u7528\u7684\u8f6f\u4ef6\u662f\u81ea\u5df1\u7f16\u8bd1\u7684\uff0c\u4f60\u4eec\u5e73\u53f0\u652f\u6301\u5417\uff1f<\/strong>
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13\u3001\u5bf9\u4e8e\u4e00\u4e9b\u5546\u4e1a\u8f6f\u4ef6\u4f8b\u5982Schr\u00f6dinger\uff0c\u4f60\u4eec\u63d0\u4f9bLicense\u5417\uff1f<\/strong>
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14\u3001\u5206\u5b50\u5bf9\u63a5\u6d41\u7a0b\u80fd\u4e0d\u80fd\u81ea\u5b9a\u4e49\uff1f\u4e0a\u4e91\u4e4b\u540e\u6bcf\u6b21\u90fd\u8981\u91cd\u65b0\u5f04\u4e00\u904d\u5417\uff1f<\/strong>
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15\u3001\u4f60\u4eec\u662f\u5426\u63d0\u4f9b\u56fa\u5b9a\u7684\u5de5\u4f5c\u6d41\u6a21\u677f\uff1f<\/strong>
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\"\"<\/figure>\n\n\n\n

16\u3001\u4f60\u4eec\u662f\u600e\u4e48\u5e2e\u52a9\u6211\u4eec\u505a\u5de5\u4f5c\u6d41\u4f18\u5316\u7684\uff1f<\/strong>
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17\u3001\u4f60\u4eec\u7684\u4e91\u5e73\u53f0\u5982\u4f55\u4e0eCADD\u5e94\u7528\u76f8\u7ed3\u5408\u9002\u914d\uff1f<\/strong>
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<\/p>\n\n\n\n

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18\u3001\u4f60\u4eec\u7684\u5e73\u53f0\u5bb9\u6613\u64cd\u4f5c\u5417\uff1f\u7528\u8d77\u6765\u4f1a\u4e0d\u4f1a\u5f88\u9ebb\u70e6\uff1f<\/strong>
\u6211\u4eec\u4e3aAIDD\/CADD\u7814\u53d1\u4eba\u5458\u63d0\u4f9b\u4e86\u4e00\u6574\u5957\u5373\u5f00\u5373\u7528\u7684\u65b0\u836f\u7814\u53d1\u73af\u5883\uff0c\u4ece\u767b\u5f55\u684c\u9762\u3001\u6253\u5f00\u5e94\u7528\u3001\u914d\u7f6e\u3001\u63d0\u4ea4\u4efb\u52a1\u3001\u81ea\u52a8\u4e0a\u4e91\u5f00\u673a\u8fd0\u884c\u4efb\u52a1\u5e76\u81ea\u52a8\u5173\u673a\u3001\u67e5\u770b\u7ed3\u679c\u8fdb\u884c\u8c03\u8bd5\u2026\u2026\u7528\u6237\u6240\u9700\u8981\u7684\u64cd\u4f5c\u4e0e\u672c\u5730\u51e0\u4e4e\u5b8c\u5168\u4e00\u81f4\uff0c\u6bcf\u4e00\u6b65\u53ea\u9700\u5728\u5e73\u53f0\u4e0a\u4f7f\u7528\u9f20\u6807\u7b80\u5355\u70b9\u9009\u5373\u53ef\u5b8c\u6210\u3002\u3001<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

 19\u3001\u6709\u4e9b\u5e94\u7528\u9700\u8981\u5148\u8dd1\u5b8c\u4e3b\u4efb\u52a1\u518d\u8dd1\u5176\u4ed6\u4efb\u52a1\uff0c\u4e0a\u4e91\u53ef\u4ee5\u667a\u80fd\u5316\u8dd1\u4efb\u52a1\u5417\uff1f<\/strong>
\u6709\u4e9b\u5e94\u7528\u5728\u8fd0\u7b97\u65f6\u5b58\u5728\u4f9d\u4ece\u673a\u5236\uff0c\u6bcf\u82e5\u5e72\u4e2a\u4efb\u52a1\u4e2d\u5305\u542b1\u4e2a\u4e3b\u4efb\u52a1\uff0c\u53ea\u6709\u5f53\u4e3b\u4efb\u52a1\u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u5176\u4ed6\u4efb\u52a1\u624d\u80fd\u5f00\u59cb\u5e76\u884c\u8fd0\u7b97\u3002
\u7531\u4e8e\u4efb\u52a1\u6709\u5148\u540e\uff0c\u6240\u4ee5\u9700\u8981\u5148\u8dd1\u4e3b\u4efb\u52a1\uff0c\u5728\u6bcf\u4e2a\u4e3b\u4efb\u52a1\u5b8c\u6210\u4e4b\u540e\u81ea\u52a8\u8c03\u5ea6\u8d44\u6e90\u5e76\u884c\u8fd0\u7b97\u5176\u4ed6\u4efb\u52a1\u3002
\u800c\u4e0d\u540c\u4efb\u52a1\u5b8c\u6210\u65f6\u95f4\u53ef\u80fd\u4e0d\u540c\uff0c\u5bf9\u8d44\u6e90\u7684\u9700\u6c42\u91cf\u53ef\u80fd\u65f6\u9ad8\u65f6\u4f4e\u6709\u6ce2\u52a8\uff0c\u6700\u7ec8\u7ed3\u675f\u5173\u673a\u65f6\u95f4\u4e5f\u4e0d\u540c\u3002
\u6211\u4eec\u4f7f\u7528Slurm\u8c03\u5ea6\u5668\u6309\u987a\u5e8f\u8c03\u5ea6\u4efb\u52a1\u6392\u961f\uff0cAuto-Scale\u529f\u80fd\u53ef\u81ea\u52a8\u76d1\u63a7\u4efb\u52a1\u548c\u8d44\u6e90\u9700\u6c42\uff0c\u52a8\u6001\u6309\u9700\u5730\u5f00\u542f\u4e0e\u5173\u95ed\u6240\u9700\u8d44\u6e90\u3002\u8be6\u7ec6\u7684\u81ea\u52a8\u5316\u8fc7\u7a0b\u53ef\u53c2\u800327\u95ee\u3002<\/p>\n\n\n\n

20\u3001\u505a\u5206\u5b50\u5bf9\u63a5\uff0c\u52a8\u4e0d\u52a8\u5c31\u662f\u51e0\u767e\u4e07\u4e0a\u5343\u4e07\u4e2a\u5206\u5b50\uff0c\u592a\u8d35\u4e86\uff0c\u6709\u8282\u7ea6\u6210\u672c\u7684\u65b9\u6848\u5417\uff1f<\/strong>
\u5206\u5b50\u5bf9\u63a5\u89c4\u6a21\u5982\u679c\u5de8\u5927\uff0c\u6709\u4ec0\u4e48\u597d\u7684\u89e3\u51b3\u529e\u6cd5\u80fd\u52a0\u5feb\u8fd9\u4e2a\u8fc7\u7a0b\uff1f\u600e\u4e48\u505a\u5230\u7684\uff1f\u5206\u5b50\u5bf9\u63a5\u7684\u4e00\u5927\u7279\u5f81\u662f\u4efb\u52a1\u6570\u91cf\u5e9e\u5927\u800c\u5355\u4e2a\u4efb\u52a1\u8ba1\u7b97\u65f6\u95f4\u77ed\uff0c\u5355\u4e2a\u5206\u5b50\u5bf9\u63a5\u7684\u65f6\u95f4\u901a\u5e38\u5728\u51e0\u5206\u949f\u4ee5\u5185\uff08\u4e0e\u53c2\u6570\u8bbe\u7f6e\u6709\u5173\uff09\u3002
\u8fd9\u4e00\u7279\u5f81\u5929\u7136\u5339\u914d\u4e91\u7aef\u7684SPOT\u5b9e\u4f8b\u3002
\u5f53\u4fbf\u5b9c\u4e14\u968f\u65f6\u53ef\u80fd\u88ab\u62a2\u5360\u4e2d\u65ad\u7684SPOT\u5b9e\u4f8b\u9047\u5230\u8ff7\u4f60\u5374\u6d77\u91cf\u7684\u5206\u5b50\u5bf9\u63a5\u4efb\u52a1\uff0c\u7b80\u76f4\u5c31\u662f\u5929\u9020\u5730\u8bbe\u7684\u4e00\u5bf9\u3002
1\u3001\u5e38\u89c4\u5206\u5b50\u5bf9\u63a5\u4efb\u52a1\u51e0\u5206\u949f\u5373\u53ef\u7b97\u5b8c\uff0c\u7279\u522b\u9002\u5408SPOT\u8fd9\u79cd\u5206\u5206\u949f\u53ef\u80fd\u88ab\u62a2\u8d70\u7684\u72b6\u6001\uff1b
2\u3001fastone\u5e73\u53f0\u5177\u5907\u81ea\u52a8\u91cd\u8bd5\u529f\u80fd\uff0c\u4e00\u4e2a\u4efb\u52a1\u88ab\u4e2d\u65ad\u53ef\u4ee5\u81ea\u52a8\u91cd\u65b0\u63d0\u4ea4\uff0c\u4efb\u52a1\u4e4b\u95f4\u4e92\u76f8\u4e0d\u5f71\u54cd\uff0c\u91cd\u65b0\u63d0\u4ea4\u5355\u4e2a\u4efb\u52a1\u5f71\u54cd\u5f88\u5c0f\u3002\u8be6\u89c1\u300a\u751f\u4fe1\u4e91\u5b9e\u8bc1Vol.3\uff1a\u63d0\u901f2920\u500d\uff01\u7528AutoDock Vina\u5bf9\u63a52800\u4e07\u4e2a\u5206\u5b50<\/a><\/strong>\u300b<\/p>\n\n\n\n

21\u3001\u4efb\u52a1\u91cf\u6bd4\u8f83\u5927\uff0c\u60f3\u63d0\u524d\u9884\u4f30\u4e00\u4e0b\u8d39\u7528\u518d\u505a\u51b3\u7b56\uff0c\u6709\u6ca1\u6709\u4ec0\u4e48\u597d\u529e\u6cd5\uff1f<\/strong>
\u6211\u4eec\u5e73\u53f0\u9884\u8bbe\u4e86\u667a\u80fd\u9884\u6d4b\u529f\u80fd\uff0c\u4ee5MOE\u4e3a\u4f8b\u3002
\u7528\u6237\u5728fastone\u5e73\u53f0\u7684\u56fe\u5f62\u5316\u64cd\u4f5c\u754c\u9762\u8fd0\u7b97MOE\u4efb\u52a1\uff0c\u5b8c\u6210\u4ee5\u4e0b\u6b65\u9aa4\uff1a
1\u3001\u7528\u6237\u4e0a\u4f20\u6570\u636e\u6587\u4ef6\uff08\u5e73\u53f0\u81ea\u52a8\u89e3\u6790\u6587\u4ef6\uff0c\u5224\u65ad\u5176\u4e2d\u5305\u542b\u7684\u5206\u5b50\u6570\u91cf\uff09
2\u3001\u7528\u6237\u8f93\u5165\u671f\u671b\u7684\u8fd0\u7b97\u65f6\u95f4\uff08\u5e73\u53f0\u63a8\u8350\u7528\u6237\u9002\u914d\u673a\u578b\u6216\u7528\u6237\u81ea\u884c\u9009\u62e9\u673a\u578b\uff09
3\u3001\u7cfb\u7edf\u5f97\u51fa\u9884\u6d4b\u6210\u672c<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u9879\u76ee\u8d1f\u8d23\u4eba\u80fd\u591f\u975e\u5e38\u65b9\u4fbf\u5730\u4f7f\u7528\u8be5\u529f\u80fd\u9884\u4f30\u9879\u76ee\u8d39\u7528\uff0c\u5b8c\u6210\u9879\u76ee\u89c4\u5212\u548c\u7533\u8bf7\u3002 <\/p>\n\n\n\n

22\u3001\u6211\u8981\u8dd1TPU\uff0c\u4f60\u4eec\u652f\u6301\u5417\uff1f<\/strong>
\u652f\u6301\u3002
\u7528\u6237\u53ef\u4ee5\u901a\u8fc7\u6211\u4eec\u5e73\u53f0\u83b7\u53d6\u5230TPU\u8d44\u6e90\u3002<\/p>\n\n\n\n

23\u3001\u6709\u65f6\u4f1a\u9047\u5230CADD\u6a21\u62df\u51fa\u7684\u7ed3\u679c\u4e0e\u5b9e\u9645\u7ed3\u679c\u6709\u4e00\u5b9a\u51fa\u5165\uff0c\u8fd9\u662f\u4e3a\u4ec0\u4e48\uff1f<\/strong>
CADD\u672c\u8eab\u662f\u6a21\u62df\u7684\u7ed3\u679c\uff0c\u901a\u8fc7\u4e0d\u65ad\u7684\u8fed\u4ee3\uff0c\u529b\u573a\u7684\u4f18\u5316\uff0c\u4f1a\u4e0d\u65ad\u63a5\u8fd1\u5b9e\u9645\u60c5\u51b5\u3002CADD\u548c\u5b9e\u9645\u7684\u5b9e\u9a8c\u6570\u636e\u76f8\u7ed3\u5408\uff0c\u53cd\u590d\u8bbe\u8ba1\u548c\u8fed\u4ee3\uff0c\u53ef\u4ee5\u8fbe\u5230\u5f88\u597d\u7684\u6548\u679c\u3002<\/p>\n\n\n\n

24\u3001\u6709\u4e9b\u4efb\u52a1\u9700\u8981\u4f7f\u7528\u5927\u91cf\u7684GPU\u8d44\u6e90\uff0c\u4f60\u4eec\u6709\u5417\uff1f<\/strong>
\u5f53\u5355\u4e2a\u4e91\u5382\u5546\u7684GPU\u8d44\u6e90\u96be\u4ee5\u6ee1\u8db3\u9700\u6c42\u65f6\uff0c\u6211\u4eec\u4f1a\u6839\u636e\u7528\u6237\u4efb\u52a1\u9700\u8981\u548c\u7279\u6027\uff0c\u8de8\u591a\u5bb6\u516c\u6709\u4e91\u5382\u5546\uff0c\u667a\u80fd\u81ea\u52a8\u5316\u8c03\u5ea6\u4e91\u7aefGPU\u5f02\u6784\u8d44\u6e90\uff0c\u4fdd\u8bc1\u7528\u6237\u5bf9GPU\u7684\u9700\u6c42\u5f97\u5230\u6ee1\u8db3\u3002<\/p>\n\n\n\n

 25\u3001GPU\u8d44\u6e90\u5f88\u8d35\uff0c\u6709\u6ca1\u6709\u8282\u7ea6\u6210\u672c\u7684\u65b9\u6848\uff1f<\/strong>
GPU\u8d44\u6e90\u5728\u4e0d\u540c\u4e91\u5382\u5546\u4e4b\u95f4\u6709\u7740\u663e\u8457\u7684\u5dee\u5f02\uff0c\u800c\u4e14\u5f80\u5f80\u8d44\u6e90\u591a\u7684\u552e\u4ef7\u9ad8\uff0c\u4fbf\u5b9c\u7684\u8d44\u6e90\u5c11\uff0c\u540c\u65f6\u517c\u987e\u6210\u672c\u548c\u6548\u7387\u662f\u5fc5\u987b\u8981\u8003\u8651\u7684\u95ee\u9898\u3002\u4ee5\u5404\u5927\u516c\u6709\u4e91\u5382\u5546\u5728\u5317\u4eac\u5730\u533a\u7684GPU\u5b9e\u4f8b\uff08V100\uff09\u6309\u9700\u4ef7\u683c\u4e3a\u4f8b\uff0c\u6700\u9ad8\u4ef7\u683c\u8d85\u8fc7\u6700\u4f4e\u4ef72\u500d\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u6211\u4eec\u5e73\u53f0\u53ef\u7efc\u5408\u8003\u91cf\u7528\u6237\u5bf9\u5b8c\u6210\u4efb\u52a1\u6240\u9700\u65f6\u95f4\u548c\u6210\u672c\u7684\u5177\u4f53\u8981\u6c42\uff0c\u5728\u591a\u4e2a\u4e91\u5382\u5546\u7684\u8d44\u6e90\u4e4b\u95f4\u9009\u62e9\u6700\u9002\u914d\u7684\u7ec4\u5408\u65b9\u6848\uff0c\u4e3a\u7528\u6237\u8de8\u5730\u533a\u3001\u8de8\u4e91\u5382\u5546\u8c03\u5ea6\u6240\u9700\u8d44\u6e90\u3002<\/p>\n\n\n\n

26\u3001\u7528Amber\u8dd1\u4efb\u52a1\uff0c\u7528GPU\u8dd1\u975e\u5e38\u5feb\uff0c\u4f46\u662f\u6709\u65f6\u5019\u4f1a\u8dd1\u5931\u8d25\uff0c\u7528CPU\u867d\u7136\u7a33\u5b9a\u4f46\u662f\u6162\uff0c\u4f60\u4eec\u600e\u4e48\u89e3\u51b3\uff1f<\/strong>
\u8fd9\u662fAmber18\u7248\u672c\u7684\u56fa\u6709\u95ee\u9898\uff0c\u5728\u4f7f\u7528GPU\u65f6\u8ba1\u7b97\u65f6\u670910-15%\u6982\u7387\u5931\u8d25\uff0c\u9700\u8981\u53ca\u65f6\u8c03\u5ea6CPU\u8d44\u6e90\u91cd\u65b0\u8ba1\u7b97\u3002\u6211\u4eec\u5e73\u53f0\u652f\u6301\u4f18\u5148\u4f7f\u7528GPU\u8ba1\u7b97\uff0c\u5f53\u4efb\u52a1\u5931\u8d25\u65f6\uff0c\u81ea\u52a8\u8c03\u7528CPU\u91cd\u65b0\u8ba1\u7b97\u3002
\u8be5\u95ee\u9898\u5df2\u5728Amber20\u4e2d\u4fee\u590d\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u56db<\/strong>\u3001\u5bf9IT\u90e8\u95e8\u6765\u8bf4\uff0c\u6709\u54ea\u4e9b\u597d\u5904\uff1f<\/strong><\/p>\n\n\n\n

27\u3001\u73b0\u5728\u516c\u53f8\u91cc\u624d\u51e0\u53f0\u673a\u5668\uff0c\u5929\u5929\u7ef4\u62a4\u5934\u5c31\u5f88\u5927\u4e86\uff0c\u4e91\u4e0a\u8fd9\u4e48\u591a\u673a\u5668\u8fd8\u4e0d\u5f97\u628a\u81ea\u5df1\u641e\u79c3\u4e86\uff1f<\/strong>
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\u4e3e\u4e2a\u4f8b\u5b50\uff0c\u6211\u4eec\u7684Auto-Scale\u529f\u80fd\u53ef\u4ee5\u81ea\u52a8\u76d1\u63a7\u7528\u6237\u63d0\u4ea4\u7684\u4efb\u52a1\u6570\u91cf\u548c\u8d44\u6e90\u7684\u9700\u6c42\uff0c\u52a8\u6001\u6309\u9700\u5730\u5f00\u542f\u548c\u5173\u95ed\u6240\u9700\u7b97\u529b\u8d44\u6e90\uff0c\u5728\u4e0d\u591f\u7684\u65f6\u5019\uff0c\u8fd8\u80fd\u6839\u636e\u4e0d\u540c\u7684\u7528\u6237\u7b56\u7565\uff0c\u81ea\u52a8\u5316\u8c03\u5ea6\u672c\u533a\u57df\u53ca\u5176\u4ed6\u533a\u57df\u7684\u76ee\u6807\u7c7b\u578b\u6216\u76f8\u4f3c\u7c7b\u578b\u5b9e\u4f8b\u8d44\u6e90\u3002\u6240\u6709\u64cd\u4f5c\u90fd\u662f\u81ea\u52a8\u5316\u5b8c\u6210\uff0c\u65e0\u9700\u7528\u6237\u5e72\u9884\u3002
\u4e0b\u56fe\u5c31\u662f\u5f00\u542fAuto-Scale\u529f\u80fd\u540e\uff0c\u7528\u6237\u67d0\u9879\u76ee\u4e00\u5468\u4e4b\u5185\u6240\u8c03\u7528\u4e91\u7aef\u8ba1\u7b97\u8d44\u6e90\u7684\u52a8\u6001\u60c5\u51b5\u3002
\u5176\u4e2d\u6a59\u8272\u66f2\u7ebf\u4e3aOD\u5b9e\u4f8b\u7684\u4f7f\u7528\u72b6\u51b5\uff0c\u7ea2\u8272\u66f2\u7ebf\u4e3aSPOT\u7684\u4f7f\u7528\u72b6\u51b5\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Auto-Scale\u529f\u80fd\u53ef\u4ee5\u6839\u636e\u4efb\u52a1\u8fd0\u7b97\u60c5\u51b5\u52a8\u6001\u5f00\u542f\u4e91\u7aef\u8d44\u6e90\uff0c\u5e76\u5728\u6ce2\u5cf0\u8fc7\u53bb\u540e\u81ea\u52a8\u5173\u95ed\uff0c\u8ba9\u8d44\u6e90\u7684\u4f7f\u7528\u968f\u7740\u7528\u6237\u7684\u9700\u6c42\u81ea\u52a8\u6269\u5f20\u53ca\u7f29\u5c0f\uff0c\u6700\u5927\u7a0b\u5ea6\u5339\u914d\u4efb\u52a1\u9700\u6c42\u3002<\/p>\n\n\n\n

28\u3001\u4f60\u4eec\u662f\u4ec0\u4e48\u5b58\u50a8\u7b56\u7565\uff1f\u8d39\u7528\u5462\uff1f<\/strong>\u51b7\u5b58\u50a8\u548c\u70ed\u5b58\u50a8\u7684\u8d39\u7528\u662f\u4e0d\u4e00\u6837\u7684\uff0c\u6211\u4eec\u4f1a\u6839\u636e\u7528\u6237\u7684\u60c5\u51b5\u63d0\u4f9b\u4e2a\u6027\u5316\u7684\u89e3\u51b3\u65b9\u6848\u3002<\/p>\n\n\n\n

29\u3001\u6570\u636e\u5907\u4efd\u7684\u9891\u7387\u5982\u4f55\uff1f\u6700\u9ad8\u53ef\u4ee5\u8fbe\u5230\u591a\u5c11\uff1f\u73b0\u6709\u7b56\u7565\u600e\u6837\uff1f<\/strong>\u9ed8\u8ba4\u6bcf\u5468\u516d\u8fdb\u884c\u6570\u636e\u5907\u4efd\uff0c\u4e5f\u53ef\u4ee5\u6839\u636e\u5ba2\u6237\u9700\u6c42\u6309\u5929\u6216\u6309\u5c0f\u65f6\u5907\u4efd\u3002<\/p>\n\n\n\n

30\u3001\u4f7f\u7528\u5e73\u53f0\u7684\u5de5\u4f5c\u4eba\u5458\u6bd4\u8f83\u591a\uff0c\u80fd\u5426\u5bf9\u6bcf\u4e2a\u4eba\u8bbe\u7f6e\u4f7f\u7528\u8d44\u6e90\u7684\u4e0a\u9650\uff1f<\/strong>
fastone\u5e73\u53f0\u7684\u6743\u9650\u548c\u89d2\u8272\u7ba1\u7406\u529f\u80fd\uff0c\u652f\u6301\u7ba1\u7406\u5458\u89d2\u8272\u5bf9\u6bcf\u4e00\u4e2a\u7528\u6237\u8fdb\u884c\u76f8\u5173\u6743\u9650\u8bbe\u5b9a\uff0c\u5305\u62ec\u9884\u7b97\u4f7f\u7528\u4e0a\u9650\u548cCPU\u6838\u6570\u4f7f\u7528\u4e0a\u9650\uff0c\u4ece\u800c\u5728\u5168\u5c40\u89d2\u5ea6\u7ba1\u63a7\u9879\u76ee\u7684\u8d44\u6e90\u6d88\u8017\u3002\u8be5\u529f\u80fd\u4e0e\u667a\u80fd\u9884\u6d4b\u914d\u5408\u4f7f\u7528\uff0c\u80fd\u591f\u4ece\u591a\u4e2a\u5c42\u9762\u5bf9\u9884\u7b97\u548c\u8d44\u6e90\u8fdb\u884c\u5168\u65b9\u4f4d\u89c4\u5212\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

31\u3001\u516c\u53f8\u91cc\u8fd8\u6709\u4e9b\u673a\u5668\u80fd\u7528\uff0c\u4f60\u4eec\u652f\u6301\u6df7\u5408\u4e91\u6a21\u5f0f\u5417\uff1f<\/strong>
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32\u3001\u4f60\u4eec\u600e\u4e48\u5b9e\u73b0\u6df7\u5408\u4e91\uff1f<\/strong>
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 33\u3001\u516c\u53f8\u91cc\u5df2\u7ecf\u6709\u673a\u5668\u4e86\uff0c\u518d\u589e\u52a0\u4e00\u5957\u4e91\u73af\u5883\uff0cIT\u7ba1\u7406\u4e0a\u4f1a\u4e0d\u4f1a\u53d8\u9ebb\u70e6\uff1f<\/strong>\u901a\u8fc7\u6211\u4eec\u53ef\u4ee5\u5728\u4e0d\u589e\u52a0\u8d1f\u62c5\u7684\u60c5\u51b5\u4e0b\u5bf9\u63a5\u591a\u4e91\uff0c\u51cf\u5c11IT\u7ba1\u7406\u538b\u529b\u3002\u6211\u4eec\u7684\u81ea\u52a8\u5316\u7ba1\u7406\u5e73\u53f0\u5f88\u5bb9\u6613\u4e0a\u624b\uff0c\u5bf9\u63d0\u5347\u7814\u53d1\u6548\u7387\u548c\u8d44\u6e90\u5229\u7528\u7387\u90fd\u6709\u5f88\u5927\u5e2e\u52a9\u3002<\/p>\n\n\n\n

34\u3001\u6211\u4eec\u516c\u53f8\u6709\u6d77\u5916\u7814\u53d1\u90e8\u95e8\uff0c\u7528\u4f60\u4eec\u5e73\u53f0\u65b9\u4fbf\u5417\uff1f<\/strong>
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\"\"<\/figure>\n\n\n\n

35\u3001\u4e91\u4e0a\u4e91\u4e0b\u7684\u5b89\u5168\u5982\u4f55\u4fdd\u969c\uff1f<\/strong>
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 36\u3001\u6570\u636e\u5b89\u5168\u5982\u4f55\u5b9e\u73b0\uff1f<\/strong>
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- END -<\/strong><\/p>\n\n\n\n

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<\/p>\n\n\n\n

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\"\"<\/figure>\n\n\n\n

\u66f4\u591a\u7535\u5b50\u4e66<\/strong>\u6b22\u8fce\u626b\u7801\u5173\u6ce8\u5c0fF\uff08ID\uff1aimfastone\uff09\u83b7\u53d6<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

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\u8fd9\u6837\u8dd1COMSOL\uff0c\u662f\u4e0d\u662f\u5c31\u53ef\u4ee5\u53d1Nature\u4e86<\/a>
Auto-Scale\u8fd9\u652f\u4ed9\u5973\u68d2\u5982\u4f55\u5927\u5e45\u63d0\u5347Virtuoso\u4eff\u771f\u6548\u7387\uff1f<\/a><\/strong>
1\u5206\u949f\u544a\u8bc9\u4f60\u7528MOE\u6a21\u62df200000\u4e2a\u5206\u5b50\u8981\u82b1\u591a\u5c11\u94b1<\/a><\/strong>
LS-DYNA\u6c42\u89e3\u6548\u7387\u6df1\u5ea6\u6d4b\u8bc4 \u2502 \u516d\u79cd\u89c4\u6a21\uff0c\u672c\u5730VS\u4e91\u7aef5\u79cd\u4e0d\u540c\u786c\u4ef6\u914d\u7f6e<\/strong><\/a>
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AI\u592a\u7b28\u4e86\u2026\u2026\u6682\u65f6<\/a><\/strong>
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\"\"<\/figure>\n\n\n\n
\"\u56fe\u7247\"\/<\/figure>\n","protected":false},"excerpt":{"rendered":"\u521b\u65b0\u836f\u5185\u5377\u4e25\u91cd\uff0c\u4e5d\u6b7b\u4e00\u751f\uff0c\u800c\u4e14\u70e7\u94b1\u901f\u5ea6\u60ca\u4eba\u3002\u4e0d\u7ba1Big Pharma\u8fd8\u662fBiotech\u90fd\u538b\u529b\u5c71\u5927\uff0c\u9500\u552e\u989d\u3001\u5229\u6da6\u8981\u6da8\uff0c\u7814\u53d1\u8d39 …","protected":false},"author":1,"featured_media":2927,"comment_status":"open","ping_status":"open","sticky":true,"template":"","format":"standard","meta":[],"categories":[3],"tags":[24,42,27,52],"class_list":["post-2924","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry","tag-cadd-aidd","tag-42","tag-qa","tag-52"],"_links":{"self":[{"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/posts\/2924","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/comments?post=2924"}],"version-history":[{"count":0,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/posts\/2924\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/media\/2927"}],"wp:attachment":[{"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/media?parent=2924"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/categories?post=2924"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fastonetech.com\/blog\/wp-json\/wp\/v2\/tags?post=2924"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}